40-Hour Whole-Body Connectome Mapping of a Mouse: A Breakthrough Imaging Technique
2025-07-16

Scientists have developed a high-speed imaging technique that can map the detailed three-dimensional connectome of a mouse's entire nervous system in just 40 hours, achieving micrometer-scale resolution. This technique utilizes a custom-built microscope to scan a cleared and labelled sample, enabling precise tracing of nerve fibers from the brain and spinal cord to organs throughout the body. This provides a powerful tool for connectomics research. Published in *Cell*, this breakthrough represents significant progress in the field and lays the foundation for future understanding of neurological diseases and the development of new treatments.
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Imaging Technology