Germline Engineering: A Roadmap to Superbabies

This article explores the potential of germline engineering to create 'superbabies.' The author recounts a 2023 conference on polygenic embryo screening in Boston, criticizing the scientific establishment's reluctance to embrace gene editing. The author and their cofounder delve into the potential of gene editing to enhance intelligence, reduce disease risk, and extend lifespan, highlighting the superior scalability of gene editing compared to embryo selection. They introduce Sergiy Velychko's 'Super-SOX' technology, which enables efficient creation of naive embryonic stem cells, opening unprecedented opportunities for gene editing. The article also explores alternative gene editing techniques, such as creating eggs and sperm from stem cells, and addresses legal and ethical challenges. Ultimately, the author calls for increased investment and research into this technology, viewing it as a 'backup plan' to potential AI risks.