Palatable Elemental Diet Shows Promise in Treating Gut Microbial Overgrowth

Cedars-Sinai researchers have developed mBiota Elemental, a palatable elemental diet (PED) that effectively reduces key gut microbiome taxa and improves symptoms in patients with small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO). A clinical trial showed normalized breath tests and symptom relief in most participants, with no serious adverse events. The improved palatability of this PED addresses a major limitation of previous elemental diets, leading to high adherence rates. This non-antibiotic approach offers a potential new treatment option for SIBO and IMO.