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Space Crystals: Overcoming Earth's Gravity for Better Drug Discovery

2025-04-14

Growing high-quality protein crystals on Earth is challenging due to gravity-induced sedimentation, convection currents, and impurity issues. In microgravity, however, these problems are significantly reduced, leading to more uniform and higher-resolution crystals. Studies show microgravity-grown crystals exhibit significant improvements in morphology, uniformity, and resolution, with major implications for drug discovery, food chemistry, and structural biology. Spark Gravity aims to lower the barrier to entry for protein crystal research by simulating microgravity environments, accelerating the research process.

Microgravity: A Unique Environment for Space Research

2025-04-13

Microgravity isn't the absence of gravity, but rather an extremely weak gravitational field (1/1000th to 1/1,000,000th of Earth's gravity). The International Space Station, contrary to popular belief, isn't in zero-G, but experiences continuous freefall, creating the sensation of weightlessness. In microgravity, fluids, cell growth, combustion, and crystal formation behave differently, offering unique experimental possibilities. Spark Gravity is focused on programmable gravity, bridging the gap in current research limited to either full gravity or zero-G environments on Earth and the ISS. Their goal is to allow scientists to control gravity as a variable, simulate lunar, Martian, or deep space environments, and conduct long-duration studies without the need for a full space station.