Kyoto U. Develops Morphine-Equivalent Painkiller Without Severe Side Effects

A Kyoto University team has developed a painkiller, 'Adriana,' comparable to morphine but lacking its serious side effects like breathing problems and addiction. This groundbreaking drug works via a different mechanism than existing opioids, potentially revolutionizing pain management. Clinical trials showed efficacy in various patients, including lung cancer surgery patients. A larger US trial is planned for 2026, with practical application aimed for 2028, offering hope for addressing the opioid crisis and improving cancer patient care.
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