Inflammation and Aging: Not a Universal Truth
A new study from Columbia University challenges the long-held belief that inflammation is a universal hallmark of aging. Researchers compared industrialized populations (Italy and Singapore) with non-industrialized Indigenous groups (Tsimane of Bolivia and Orang Asli of Malaysia). They found that while 'inflammaging' (chronic, low-grade inflammation associated with aging) was prevalent in industrialized societies and linked to chronic diseases, it wasn't consistently observed in the Indigenous groups. In these populations, inflammation was more strongly correlated with infection rates than age. This suggests that inflammaging may be a byproduct of industrialized lifestyles rather than an inherent part of the aging process, opening up new avenues for intervention and highlighting the importance of considering context-specific factors in aging research.
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