Bacteria Build Living Gels in Polymers: A New Twist on Biofilms

Caltech and Princeton University scientists have discovered that bacteria growing in polymer solutions, like mucus, form long, intertwined cables—a kind of ‘living Jell-O.’ This is significant for understanding diseases like cystic fibrosis, where thickened lung mucus fosters dangerous bacterial infections. The discovery also has implications for studying biofilms (the slimy coatings on surfaces) and their industrial impacts. The researchers found that external pressure from the polymers forces the bacterial cells together. A theoretical model accurately predicts when these cable structures will form. The reason for cable formation remains a mystery: it may be a bacterial defense mechanism or conversely, a way for the body to expel the infection more easily. This unexpected finding opens up new avenues of research into bacterial growth and biofilm control.
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