Brazilian Biomedical Research Reproducibility Crisis: Half of Experiments Fail to Replicate

A large-scale study involving over 50 Brazilian research teams found that over half of biomedical experiments failed to reproduce. The teams selected three common biomedical methods and replicated experiments from papers published between 1998 and 2017. Results showed only 21% of experiments met reproducibility criteria, with original papers reporting effect sizes 60% larger on average than replications. This highlights reproducibility issues in Brazilian biomedical research and provides crucial evidence for improving research practices and policies.