Fitness and Mortality: A Large Study Reveals Surprising Correlation
2025-05-18
A study of 1.1 million Swedish men challenges the long-held association between fitness and reduced mortality. Researchers found that while those with high fitness levels in adolescence had lower overall mortality rates, they also had similarly lower rates of accidental death, suggesting other confounding factors. Negative control outcome analysis and sibling comparison design confirmed potential bias, indicating an overestimation of fitness's impact on cardiovascular disease and cancer mortality. The study stresses the need for large-scale interventions to be based on reliable estimates, avoiding the risk of inflated expectations.
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observational study