Is This Aging Biotech Actually Tackling Aging?
The longevity biotech space is booming, attracting billions in investment. However, not all claims of aging therapies hold water. This article explores what constitutes a truly effective anti-aging treatment: preventing multiple age-related diseases, preserving healthy function, and reversing the aging process. It cautions against focusing solely on aging biomarkers or “aging clocks,” emphasizing that correlation doesn't equal causation. Effective therapies should target prevalent age-related issues like muscle loss, immune dysfunction, and metabolic disorders, using measurable short-term clinical endpoints. The article stresses the importance of using aged organisms, spontaneous disease models, and human samples, and proposes promising strategies like delaying, replacing, restoring, and pausing aging.