Scientists Map the Complete Neural Pathway for Sensing Cool Temperatures
2025-08-04
Researchers at the University of Michigan have, for the first time, mapped the entire neural pathway responsible for sensing cool temperatures, from the skin to the brain. This groundbreaking discovery reveals a dedicated pathway for cool temperatures, separate from the pathway for hot temperatures, highlighting evolution's elegant solution for precise thermal perception. A key component is a spinal cord amplifier; without it, the cool signal is lost. This research not only deepens our understanding of fundamental biology but also holds significant implications for treating cold-related pain, such as that experienced by chemotherapy patients.