Neurobiological Substrates of Altered States of Consciousness Induced by High Ventilation Breathwork
A new study investigates the neurobiological mechanisms underlying altered states of consciousness (ASCs) induced by high-ventilation breathwork (HVB) combined with music. Researchers conducted three experiments (remote, MRI, and psychophysiological lab) measuring participants' subjective experiences, brain blood flow, and heart rate variability. Results showed HVB caused reduced brain blood flow, particularly in the posterior insula and parietal operculum, correlating with the intensity of 'Oceanic Boundlessness' (a key aspect of ASCs). Increased blood flow in the amygdala and hippocampus also correlated with this experience. This research offers valuable insights into the neural mechanisms of HVB-induced ASCs and potential therapeutic applications for mental health disorders.