PubPeer Review: TRF2-S Protein Regulates Axonal mRNA Transport

2025-01-16

A PubPeer post discusses a research article on TRF2-S, a novel RNA- and FMRP-binding protein crucial for regulating axonal mRNA transport and presynaptic plasticity. Published in Nature Communications, the study reveals how TRF2-S influences neuronal growth and function by impacting mRNA trafficking and local translation. This research sheds light on neural mechanisms and potentially offers new avenues for neurological disease treatment.