Concussions May Reactivate Herpes Virus, Triggering Alzheimer's
2025-02-01
Researchers at Tufts University used a 3D mini-brain model to demonstrate that simulated concussions can reactivate latent herpes simplex virus type 1 (HSV-1) in brain tissue, leading to Alzheimer's-like inflammation, amyloid plaques, and neuron death. This research connects HSV-1 infection, head trauma, and Alzheimer's for the first time, providing new evidence for the microbial theory of Alzheimer's and suggesting antiviral drugs as a potential preventative treatment. The findings indicate that head injuries, such as concussions, may reactivate dormant HSV-1, increasing the risk of Alzheimer's disease.