CRISPR Gene Editing: From Bacterial Immunity to Human Therapies

2025-06-19
CRISPR Gene Editing: From Bacterial Immunity to Human Therapies

Victoria Gray's successful treatment for sickle cell anemia using CRISPR gene editing marks a new era for gene therapy. This article delves into the diverse CRISPR systems, including Cas9, Cas12, Cas13, base editors, and prime editors, explaining their mechanisms, advantages, disadvantages, and clinical applications. Evolving from a natural bacterial defense mechanism, CRISPR technology is now widely used in disease treatment, agriculture, and sustainability efforts, but faces challenges such as high costs and off-target effects. The discovery and improvement of more novel gene editing tools will further drive the development of this field.