Slimy Brain Barrier Holds Key to Combating Ageing
2025-03-02
A study in mice reveals that a slimy barrier lining brain blood vessels, composed of mucins, deteriorates with age, potentially allowing harmful molecules into brain tissue and triggering inflammation. Restoring this barrier through gene therapy reduced brain inflammation and improved learning and memory in aged mice. This research highlights a potential therapeutic target for age-related diseases like Alzheimer's.