Platelet-T Cell Crosstalk in Cancer Metastasis: A Mouse Model Study

2025-03-09
Platelet-T Cell Crosstalk in Cancer Metastasis: A Mouse Model Study

This study uses multiple mouse models to investigate the crucial role of platelet-T cell interactions in cancer metastasis. Through in vivo and in vitro experiments, combined with techniques such as flow cytometry, RNA sequencing, and immunofluorescence microscopy, researchers revealed the mechanisms of specific molecular pathways (e.g., ARHGEF1 and TXA2) in regulating this process. The results suggest that targeting these pathways may offer novel therapeutic strategies for cancer treatment.