Ancient DNA Extraction from Paleolithic Artifacts Reveals Clues to 45,000-Year-Old Human Activities

2025-03-10
Ancient DNA Extraction from Paleolithic Artifacts Reveals Clues to 45,000-Year-Old Human Activities

A groundbreaking study successfully extracted ancient DNA from Paleolithic artifacts unearthed at the French sites of Quinçay and Les Cottés, and from Bacho Kiro Cave in Bulgaria and Denisova Cave in Russia. Researchers developed a non-destructive DNA extraction method using sodium phosphate buffer at varying temperatures to gradually release DNA, minimizing damage to the artifacts. This method yielded both human and animal DNA, offering invaluable genetic insights into human activities and behaviors dating back 45,000 years.