Immune Molecule IL-17: The Secret Driver of Anxiety and Sociability

Research from MIT and Harvard Medical School reveals that the immune molecule IL-17, acting on the amygdala and somatosensory cortex, respectively induces anxiety and promotes social behavior. This study highlights the close interplay between the immune and nervous systems, suggesting IL-17 may have originally evolved as a neuromodulator before being co-opted by the immune system to promote inflammation. The findings offer a novel therapeutic approach for neurological conditions like autism or depression, potentially influencing brain function by targeting the immune system.